Core Nutritionals Flex
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Description
Don’t leave your recovery to chance. Core FLEX is an ultra-potent combination of 11 clinically supported ingredients designed to maintain strong, healthy tendons and ligaments. This all-in-one formula delivers the benefits of single-ingredient joint supplements while providing the synergy of a complete joint health system.
8 tablets per serving • 30 servings per container • Soft tissue support
We all know the dilemma: spend money on something fun, or fix that strange noise coming from the engine? Most people choose the fun option—until the engine fails. The same logic applies to your body. Daily life, and especially intense training, places constant stress on your joints, tendons, and ligaments. As you lift heavier, run farther, and push harder, these tissues require ongoing maintenance. Ignoring the “engine noise” only leads to bigger problems.
Core FLEX provides a superior maintenance solution for soft tissue health. Its 11 ingredients are included at clinical dosages and supported by research to help preserve joint integrity, improve mobility, and support healthy connective tissue function.
Physiological Properties & Ingredient Effects
Glucosamine & Chondroitin
Glucosamine and chondroitin are naturally occurring components of cartilage and connective tissue.
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Glucosamine, an amino sugar, is a precursor to glycosaminoglycans—key molecules in cartilage production, joint cushioning, and lubrication.
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Chondroitin sulfate, a sulfur-rich glycosaminoglycan, provides structural support, stability, and hydration to cartilage, enabling smooth joint movement.
Supplementing with both ingredients supports joint repair, thickness, and resilience—especially in damaged or stressed joints.
Methylsulfonylmethane (MSM)
MSM is an organosulfur compound found naturally in the body and known for supporting cellular communication and mobility.
Clinical data shows:
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Improvements of 20–35% in joint function scores (WOMAC)
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Support for flexibility, reduced discomfort, and general joint performance
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Strong antioxidant properties and potential to support healthy inflammation responses
A 2011 meta-analysis confirmed that most MSM trials show meaningful improvements over placebo.
Cissus quadrangularis
Cissus quadrangularis (CQ) has thousands of years of documented use in Ayurvedic and Siddha medicine for bone healing, pain relief, and strengthening connective tissue.
Modern research suggests CQ:
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Reduces pro-inflammatory cytokines
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Modulates the glucocorticoid system
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Stimulates osteoblast (bone-forming cell) activity
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Increases mucopolysaccharides—key precursors to bone mineralization (think of them as the “paper mache base” before the structure hardens)
CQ supports bone health, tendon integrity, and recovery from mechanical stress.
Black Cherry Extract
Black cherry extract contains high levels of anthocyanins, potent antioxidants that help regulate inflammation and support joint comfort.
It is also rich in catechins, chlorogenic acid, and flavonol glycosides—compounds traditionally used to support joint mobility and healthy uric acid balance.
Turmeric (95% Curcumin)
Turmeric has been used for millennia in traditional medicine. Modern science attributes its benefits primarily to curcumin, an exceptionally strong anti-inflammatory compound.
Curcumin:
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Inhibits cyclooxygenase and lipoxygenase (enzymes producing inflammatory molecules like prostaglandins and leukotrienes)
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Suppresses NF-κB, a transcription factor responsible for driving inflammation, soft tissue degeneration, and autoimmune activity
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Supports overall joint comfort and soft tissue integrity
Core FLEX uses a highly standardized 95% curcumin extract to match clinical research—not the ~5% curcumin found in raw turmeric.
Boswellia (37.5% Boswellic Acids)
Boswellia resin, long used in Indian medicine, contains boswellic acids that:
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Inhibit leukotriene synthesis
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Reduce NF-κB activity
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Support joint mobility and healthy inflammation responses
Its mechanisms complement curcumin for a powerful joint-support synergy.
Bromelain (2400 GDU/g)
Bromelain is a proteolytic enzyme derived from pineapple stems.
Research shows, bromelain may:
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Support healthy inflammation responses
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Assist circulation and tissue repair
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Promote faster recovery following stress or procedures
Its multi-pathway activity makes it an excellent addition to joint and soft-tissue formulas.
Vitamin C
Vitamin C functions as a powerful antioxidant and immune-supportive nutrient.
A UC Berkeley study found that 500 mg of vitamin C (the dose in Core FLEX) reduced C-reactive protein (CRP)—a key inflammation marker—by 24%.
Vitamin C also supports collagen formation, joint tissue repair, and protection against oxidative stress.
Vitamin D3
Vitamin D3 plays an essential role in:
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Bone mineralization
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Muscle protein synthesis
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Immune and cardiovascular health
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Healthy inflammatory responses in joints and connective tissue
Most individuals do not obtain adequate D3 from sunlight or diet alone, making supplementation necessary for optimal joint health.
Piperine (95%)
Piperine, a black pepper extract, enhances nutrient absorption—especially curcumin uptake. Without piperine, curcumin absorption is significantly reduced due to poor bioavailability.
Including piperine ensures full potency of FLEX’s curcumin component.
The FLEX Difference
Core FLEX delivers what most products only promise:
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11 clinically dosed ingredients
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Multi-pathway support for joints, tendons, ligaments, and soft tissue
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Synergy between anti-inflammatory, structural, and recovery-focused compounds
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The complete joint health system—combined into one formula
Your training pushes limits. Core FLEX helps your body keep up.
Ingredients
Cissus, Boswellia, Chondroitin
Directions
8 tablets
Warnings
WARNING: NOT INTENDED FOR USE BY PERSONS UNDER THE AGE OF 18. If you are pregnant or breast feeding, consult your healthcare professional before using this product. People with known medical conditions and/or taking any prescription drugs should consult with a licensed physician prior to taking. KEEP OUT OF REACH OF CHILDREN. Contains 200 mg of active caffeine per serving.
Support Your Goals
Improved joint function and strength,Promotes healthy tendons and strengthens cartilage, Contains antioxidants to help boost recovery
About the Brand
The Core Nutritionals® brand is built on and represented through an everyday adherence to the CRUSH IT® mentality. From the gym to the stage, at home, and in our relationships with colleagues, customers, and industry affiliates, this commitment never waivers in those who adhere to this mentality. Like our customers, we strive for perfection and success but always remain committed to our unwavering integrity and values while helping to bring out the best in others.
Core Nutritionals Flex
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