Explore the powerful multi-benefits Bodybuilding.com’s Signature Triple Carnitine.
Master Coach Ken Yu
January 2, 2025
What is Carnitine?
Carnitine is a compound naturally produced by the kidneys and liver. This powerhouse compound stored in skeletal muscle, and the heart and brain asits primary function is to move long-chain fatty acids into mitochondria to produce energy.[1] Carnitine can be consumed through red meat, dairy products, avocados, and soybeans. However, many people are not able to consume enough through their diet thereby making fat metabolism more difficult.[2]
The Many Benefits of Carnitine Supplementation
Carnitine supplementation has been extensively studied and generally well tolerated with dosages between 500mg to 3,000mg showing benefits related to weight loss, increased fat metabolism, energy production, improved exercise performance, cognitive function, and even helping with infertility.[3] Let’s explore more of the unique benefits of carnitine below.
Support for Weight Loss and Fat Metabolism
Carnitine helps the body convert fat into energy. Many individuals can supplement to help with weight management, fat oxidation, and improve energy levels.[4] A meta-analysis of scientific literature found that a daily dose of 1,500 mg or more of carnitine maximized weight and fat loss in adults.[5-6]
Boosting Energy and Exercise Performance
Studies have shown that carnitine supplementation can improve exercise performance, increase muscle mass, decrease muscle soreness, and improve higher cognitive function, especially in vegetarians, overweight individuals, and older adults.[7-8] Also, carnitine can help with branched-chain amino acids (BCAA) metabolism, making it a perfect complement to this supplement.[9]
Cognitive and Mental Health Benefits
Recent studies have linked carnitine with cognitive benefits. Carnitine, particularly acetyl-L-carnitine, has been shown to improve cognitive function, mood stabilization, and other potential effects on brain health.[10-11]
Clinical Applications
Carnitine has been used to treat individuals with cardiovascular issues to help increase metabolism in heart cells.[12] Carnitine supplementation has also been shown to help with male infertility issues by increasing sperm motility in men.[13]
Why Triple Carnitine?
Bodybuilding.com’s Signature Triple Carnitine has three different forms of carnitine to help maximize different aspects of the supplement and provide optimal multi-benefits.First, L-Carnitine Tartrate can aid in maximizing fat metabolism. Second, Acetyl L-Carnitine HCI can boost your cognitive focus. Last but not lead, L-Carnitine Fumarate focuses on increased energy to help take your workouts and daily performance to the next level.
References
- Belay B, Esteban-Cruciani N, Walsh CA, Kaskel FJ. The use of levo-carnitine in children with renal disease: a review and a call for future studies. Pediatr Nephrol. 2006 Mar;21(3):308-17. doi: 10.1007/s00467-005-2085-4. Epub 2005 Dec 23. PMID: 16374652.
- https://ods.od.nih.gov/factsheets/Carnitine-HealthProfessional
- Hathcock JN, Shao A. Risk assessment for carnitine. Regul Toxicol Pharmacol. 2006 Oct;46(1):23-8. doi: 10.1016/j.yrtph.2006.06.007. Epub 2006 Aug 9. PMID: 16901595.
- Pistone G, Marino A, Leotta C, Dell'Arte S, Finocchiaro G, Malaguarnera M. Levocarnitine administration in elderly subjects with rapid muscle fatigue: effect on body composition, lipid profile and fatigue. Drugs Aging. 2003;20(10):761-7. doi: 10.2165/00002512-200320100-00004. PMID: 12875611.
- Asadi M, Rahimlou M, Shishehbor F, Mansoori A. The effect of l-carnitine supplementation on lipid profile and glycaemic control in adults with cardiovascular risk factors: A systematic review and meta-analysis of randomized controlled clinical trials. Clin Nutr. 2020 Jan;39(1):110-122. doi: 10.1016/j.clnu.2019.01.020. Epub 2019 Feb 22. PMID: 30850271.
- Talenezhad N, Mohammadi M, Ramezani-Jolfaie N, Mozaffari-Khosravi H, Salehi-Abargouei A. Effects of l-carnitine supplementation on weight loss and body composition: A systematic review and meta-analysis of 37 randomized controlled clinical trials with dose-response analysis. Clin Nutr ESPEN. 2020 Jun;37:9-23. doi: 10.1016/j.clnesp.2020.03.008. Epub 2020 Apr 18. PMID: 32359762.
- Askarpour M, Hadi A, Miraghajani M, Symonds ME, Sheikhi A, Ghaedi E. Beneficial effects of l-carnitine supplementation for weight management in overweight and obese adults: An updated systematic review and dose-response meta-analysis of randomized controlled trials. Pharmacol Res. 2020 Jan;151:104554. doi: 10.1016/j.phrs.2019.104554. Epub 2019 Nov 17. PMID: 31743774.
- Sawicka AK, Renzi G, Olek RA. The bright and the dark sides of L-carnitine supplementation: a systematic review. J Int Soc Sports Nutr. 2020 Sep 21;17(1):49. doi: 10.1186/s12970-020-00377-2. PMID: 32958033; PMCID: PMC7507632.
- Hoppel C. The role of carnitine in normal and altered fatty acid metabolism. Am J Kidney Dis. 2003 Apr;41(4 Suppl 4):S4-12. doi: 10.1016/s0272-6386(03)00112-4. PMID: 12751049.
- Benton D, Donohoe RT. The influence on cognition of the interactions between lecithin, carnitine and carbohydrate. Psychopharmacology (Berl). 2004 Aug;175(1):84-91. doi: 10.1007/s00213-004-1773-2. Epub 2004 Feb 4. PMID: 14760514.
- Malaguarnera M, Gargante MP, Cristaldi E, Colonna V, Messano M, Koverech A, Neri S, Vacante M, Cammalleri L, Motta M. Acetyl L-carnitine (ALC) treatment in elderly patients with fatigue. Arch Gerontol Geriatr. 2008 Mar-Apr;46(2):181-90. doi: 10.1016/j.archger.2007.03.012. Epub 2007 Jul 20. PMID: 17658628.
- Brass EP, Koster D, Hiatt WR, Amato A. A systematic review and meta-analysis of propionyl-L-carnitine effects on exercise performance in patients with claudication. Vasc Med. 2013 Feb;18(1):3-12. doi: 10.1177/1358863X12467491. Epub 2013 Jan 15. PMID: 23321261.
- Zhang X, Cui Y, Dong L, Sun M, Zhang Y. The efficacy of combined l-carnitine and l-acetyl carnitine in men with idiopathic oligoasthenoteratozoospermia: A systematic review and meta-analysis. Andrologia. 2020 Mar;52(2):e13470. doi: 10.1111/and.13470. Epub 2019 Nov 7. PMID: 31701550.
